Synthesis, Characterization, and Biocidal Studies of the Newly Synthesized Di- and Triorganotin(IV) Complexes with n-Butylhydrogen Phthalate

Authors : Saqib ALI, Saira SHAHZADI

Pages : 371-387

View : 21 | Download : 8

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Di-insert ignore into journalissuearticles values(1, 3, 8); and triorganotininsert ignore into journalissuearticles values(IV); complexes insert ignore into journalissuearticles values(2, 5, 7); with the general formula RnSnL4-n, where R = Me, Et, n-Bu, n-Oct, Ph, and Bz, and L = the n-C4H9OCOC6H4COO- monoanionic ligand have been synthesized by the reaction of the silver salt of the n-butylhydrogen phthalate with di- and triorganotin chloride in dry chloroform. However, di-n-butyl- and di-n-octyltininsert ignore into journalissuearticles values(IV); derivatives insert ignore into journalissuearticles values(4 and 6, respectively); were synthesized by the reaction of the corresponding organotininsert ignore into journalissuearticles values(IV); oxide with n-butylhydrogen phthalate in dry toluene. All the synthesized complexes were characterized by elemental analysis, FT-IR, multinuclear insert ignore into journalissuearticles values(1H, 13C, 119Sn); NMR, and mass spectrometric techniques to assess the binding mode of the n-butylphthalate insert ignore into journalissuearticles values(n-C4H9OCOC6H4COO-); anion. The diorganotininsert ignore into journalissuearticles values(IV); derivatives were found to adopt distorted octahedral and triorganotininsert ignore into journalissuearticles values(IV); n-butylphthalates and to have linear, polymeric trigonal bipyramidal structures in which n-butylphthalate is a monoanionic bidentate coordinating through the Cinsert ignore into journalissuearticles values(O);O group. The biocidal activity and LD50 values of the synthesized compounds are also reported. Some complexes exhibited good activity comparable to that of standard drugs. Furthermore, triorganotininsert ignore into journalissuearticles values(IV); derivatives exhibited significantly better activity than the diorganotininsert ignore into journalissuearticles values(IV); derivatives.
Keywords : Organotin IV, complexes, n butylhydrogen phthalate, spectral characterization, biological activity