A Convenient Method for the Preparation of 2-Aminobenzophenone Derivatives under Ultrasonic Irradiation

Authors : Javad SAFAEIGHOMI, Manouchehr FADAEIAN, Alireza HATAMI

Pages : 89-95

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A quick and convenient method for the preparation of 2-aminobenzophenone derivatives is described. This approach consists of the nucleophilic substitution reaction of nitrobenzenes by phenylacetonitrile under conventional and ultrasonic conditions followed by reduction of the produced 2,1-benzisoxazole to 2-aminobenzophenone. This 2-step reaction was studied by changing the reaction parameters insert ignore into journalissuearticles values(reaction temperature, ultrasound power, and reaction time);. The results clearly demonstrated that using ultrasound irradiation results in a high yield within a short reaction time.
Keywords : Turk J Chem, 31, 2007, 89 95 Turk J Chem, vol 31, iss 1