Spectroscopic Characterisation and Biological Applications of Organotin(IV) Derivatives of 3-(N-Naphthylaminocarbonyl)-2-propenoic Acid

Authors : Sajjad AHMED, Moazzam Hussain BHATTI

Pages : 471-482

View : 13 | Download : 10

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :In an effort to develop new organotin materials for investigation and biocidal evaluation, a series of compounds with the general formula R4 - nSnLn insert ignore into journalissuearticles values(where R = CH3, n-C4H9, C6H5, C6H5CH2 and L = 3-insert ignore into journalissuearticles values(N-naphthylaminocarbonyl);-2-propenoic acid); were synthesised, and characterised by elemental analysis, IR, multinuclear insert ignore into journalissuearticles values(1H, 13C and 119Sn); NMR, 119mSn Mössbauer spectroscopy and mass spectrometry. The biological activity of these compounds against various bacteria and fungi was investigated. All of the compounds were active against the fungi tested with a few exceptions. These compounds also showed significant antibacterial activity. LD50 data show that the investigated compounds have significant toxicity.
Keywords : Organotin IV, carboxylates, biological studies, spectroscopic studies