Synthesis and Antimicrobial Activity of Some New 3-Substituted Benzyl-5-(4-chloro-2-piperidin-1yl-thiazole-5-yl-methylene)-thiazolidine-2,4-dione Derivatives

Authors : Meltem Ceylan ÜNLÜSOY, Oya Bozdağ DÜNDAR

Pages : 355-360

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A new series of thiazolyl thiazolidine-2,4-dione insert ignore into journalissuearticles values(Va-f); were synthesized and their structures were elucidated by IR, 1H-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.
Keywords : Thiazolidine 2, 4 diones, thiazole derivatives, antimicrobial activities