Synthesis, Characterization and Genotoxicity of Platinum(II)Complexes With Subtituted Benzimidazole Ligands

Authors : Öztekin ALGÜL, Berrin ÖZÇELİK

Pages : 607-615

View : 19 | Download : 9

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Five Ptinsert ignore into journalissuearticles values(II); complexes with the ligands 2-ethyl-/ or-benzyl-/ or-phenoxymethyl- and 1-methyl-2-hydroxymethyl- and 1-methyl-2-phenyl- benzimidazoles were synthesized and characterized by elemental analysis, and IR and 1H-NMR spectra and evaluated for their in vitro genotoxic activities by Rec-Assay test. Based on the data obtained in this study, the Ptinsert ignore into journalissuearticles values(II); complexes tested might be taken into consideration as promising antitumor compounds.
Keywords : Benzimidazol, Platinum II, complexes, In vitro genotoxic activity, Rec Assay test