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  • Turkish Journal of Chemistry
  • Volume:29 Issue:6
  • A New Approach Towards (\pm)-4-Ipomeanol and Its 2-Furyl Regioisomer

A New Approach Towards (\pm)-4-Ipomeanol and Its 2-Furyl Regioisomer

Authors : Jürgen KRAUSS, Franz BRACHER and Doris UNTERREITMEIER
Pages : 635-640
View : 18 | Download : 8
Publication Date : 0000-00-00
Article Type : Research Paper
Abstract :The cytotoxic furan derivative insert ignore into journalissuearticles values(\pm);-4-ipomeanol insert ignore into journalissuearticles values(1); and its regioisomer insert ignore into journalissuearticles values(8); were prepared in a new and efficient way starting from commercially available furan derivatives. In both cases the key step was a regioselective solvolysis of the terminal double bond with trifluoroacetic anhydride and boron trifluoride. The resulting compounds were tested in an agar diffusion assay against several bacteria and fungi, but did not show significant activity.
Keywords : pm, 4 ipomeanol, solvolysis, antimicrobial activity

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