Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum

Authors : Zeliha Ş AKDEMİR, İ İrem TATLI

Pages : 227-234

View : 22 | Download : 10

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Three iridoid glucosides, 8-O-acethylharpagide insert ignore into journalissuearticles values(1);, harpagoside insert ignore into journalissuearticles values(2);, and 6-O-vanilloylajugol insert ignore into journalissuearticles values(3);, were isolated from the roots of Verbascum lasianthum Boiss. ex Bentham. In addition, 2 phenylethanoid glycosides, verbascoside {=acteoside, [b -insert ignore into journalissuearticles values(3,4-dihydroxyphenyl);-ethyl]-insert ignore into journalissuearticles values(3` -O-a -L-rhamnopyranosyl);-insert ignore into journalissuearticles values(4` -O-caffeoyl);-b -D-glucopyranoside} insert ignore into journalissuearticles values(4); and poliumoside {= [b -insert ignore into journalissuearticles values(3,4-dihydroxyphenyl);-ethyl]-insert ignore into journalissuearticles values(3`,6` -O-a -L-dirhamnopyranosyl);-insert ignore into journalissuearticles values(4` -O-caffeoyl);-b -D-glucopyranoside} insert ignore into journalissuearticles values(5);, were also isolated. The structures of all compounds were established by spectroscopic evidence insert ignore into journalissuearticles values(UV, IR, 1D and 2D NMR, LC-ESIMS);. Compounds 2-5 demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl insert ignore into journalissuearticles values(DPPH); radical in TLC autographic assays.
Keywords : Verbascum lasianthum, Scrophulariaceae, iridoid glucosides, 8 O acethylharpagide, harpagoside, 6 O vanilloylajugol, phenylethanoid glycosides, verbascoside acteoside, poliumoside, radical scavenging activ