Synthesis, Characterization and Primary Antituberculosis Activity Evaluation of 4-(3-Coumarinyl)-3-benzyl-4-thiazolin-2-one Benzylidenehydrazones

Authors : Aysel GÜRSOY, Nilgün KARALI

Pages : 545-552

View : 22 | Download : 14

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :In this study a new series of 4-insert ignore into journalissuearticles values(3-coumarinyl);-3-benzyl-4-thiazolin- 2-one benzylidenehydrazones 3a-t was synthesized. Structures of the title compounds were elucidated by elemental analyses and spectrometric data insert ignore into journalissuearticles values(IR, 1H-NMR, 13C-NMR and EIMS);. 3a-t were evaluated for antituberculosis activity against Mycobacterium tuberculosis} H37Rv in BACTEC 12B medium using the BACTEC 460 radiometric system.
Keywords : Coumarinylthiazolines, synthesis, antituberculosis activity