Voltammetric Determination of Salbutamol Based on Electrochemical Oxidation at Platinum and Glassy Carbon Electrodes

Authors : Niyazi YILMAZ, Sibel A ÖZKAN, Bengi USLU

Pages : 175-182

View : 25 | Download : 9

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The oxidative behavior of salbutamol was studied as a function of pH at platinum and activated glassy carbon electrodes. Between pH 1.9 and 12.0, the drug was characterized by a single oxidation step at both electrodes. The process was found to be dependent on the nature and the pH of the supporting elctrolyte. The procedure yielded a linear concentration range of 1 \times 10-4 to 1 \times 10-3 M and 2 \times 10-5 to 1 \times 10-3 M in 0.2 M sulphuric acid and a phosphate buffer of pH 6, at platinum and glassy carbon electrodes, respectively. The method was used for the determination of salbutamol in pharmaceutical dosage forms. Keywords: Salbutamol, platinum and glassy carbon electrodes, pharmaceutical dosage forms, voltammetry.
Keywords : Turk J Chem, 22, 1998, 175 182 Turk J Chem, vol 22, iss 2