Synthesis of new oxindole derivatives containing benzothiazole and thiazolidinone moieties using nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as catalyst

Authors : ROBABEH BAHARFAR, NARGES SHARIATI

Pages : 235-0

Doi:10.3906/kim-1408-26

View : 17 | Download : 8

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A facile one-pot synthesis of novel oxindole derivatives bearing benzothiazolylmethyl-2-thioxothiazolidin-4-one was accomplished via one-pot reaction of 5-oxoindolinylidene rhodanine-3-acetic acid derivatives, 2-aminothiophenol, and triphenyl phosphite in the presence of tetrabutylammonium bromide insert ignore into journalissuearticles values(TBAB); and nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride insert ignore into journalissuearticles values(NSB-DBU); as heterogeneous reusable nanocatalyst. The target compounds were obtained in excellent yields insert ignore into journalissuearticles values(85%--92%); and short reaction times under fairly mild reaction conditions.
Keywords : Oxindole derivatives, benzothiazoles, 4 thiazolidinones, nano silica bonded 5 n propyl octahydro pyrimido 1, 2 a azepinium chloride, nano silica supported catalyst