New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents

Authors : NADER NOROOZI PESYAN, DAVOUD SOLEIMANI, NIMA HOSSEINI JAZANI

Pages : 998-1011

View : 14 | Download : 9

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A series of new tetrazolic azo dyes based on insert ignore into journalissuearticles values(thio);barbiturate and electron-rich aromatics were synthesized in excellent yield. The electron-donor and tetrazole ring moieties were linked by a $p$-phenylazo bridge and the structural characterizations were achieved by FT IR, $^{1}$H and $^{13}$C NMR, and UV-visible spectrometry. The antibacterial activity of the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely \textit{Acinetobacter calcoaceticus} insert ignore into journalissuearticles values(ATCC23055);, \textit{Escherichia coli} insert ignore into journalissuearticles values(ATCC2592);, \textit{Pseudomonas aeruginosa} insert ignore into journalissuearticles values(ATCC27853);, and \textit{Staphylococcus aureus} insert ignore into journalissuearticles values(ATCC25923);. As a result, potential antimicrobial effects were seen for some of the synthesized compounds.
Keywords : Tetrazole, azo dye, thio, barbituric acid, antimicrobial effect