Synthetic approaches towards the synthesis of beta-blockers (betaxolol, metoprolol, sotalol, and timolol)

Authors : FURQAN AHMAD SADDIQUE, AMEER FAWAD ZAHOOR, MUHAMMMAD YOUSAF, MUHAMMMAD IRFAN, MATLOOB AHMAD, ASIM MANSHA, ZULFIQAR ALI KHAN, SYED ALI RAZA NAQVI

Pages : 193-224

View : 19 | Download : 7

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Numerous efficient synthetic methodologies have been elaborated for the synthesis of $\beta $-blockers since the introduction of propranolol insert ignore into journalissuearticles values(a beta-blocker); in 1968. In this review, focus is placed on the more concise asymmetric and bioenzymatic synthetic approaches attempted towards the synthesis of beta-blockers insert ignore into journalissuearticles values(betaxolol, metoprolol, sotalol, and timolol);.
Keywords : Beta blockers, cardiovascular activity, antiglaucoma agent, biotransformations