Stereoselective and regioselective synthesis of $N$-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates

Authors : Ayşen Köseceli ÖZENÇ, İlhami ÇELİK, ŞULE KÖKTEN

Pages : 323-334

View : 16 | Download : 8

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :$N$-Substituted methyl 2-insert ignore into journalissuearticles values(insert ignore into journalissuearticles values(azolyl);methyl);-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis--Hillman acetates and a suitable acylazole in the presence of K$_{2}$CO$_{3}$ as a base catalyst. The targeted $N$-substituted azole acrylates were efficiently obtained in good yields insert ignore into journalissuearticles values(39%-89%);.
Keywords : Imidazole, benzimidazole, benzotriazole, Baylis Hillman acetates, N substituted azole acrylates