Synthesis, characterization, and antimicrobial activities of novel monosaccharide-containing Schiff base ligands

Authors : Fatma TELLİ, Stephen Thomas ASTLEY, AZİZE YEŞİM SALMAN

Pages : 370-380

View : 15 | Download : 13

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Four new chiral Schiff base ligands insert ignore into journalissuearticles values(3a-4a, 3b-4b); have been prepared using aminoisopropylidene derivatives of glucose and aminochloralose derivatives of mannose. The synthesized compounds 1 and 2 were characterized by nuclear magnetic resonance insert ignore into journalissuearticles values($^{1}$H and $^{13}$C NMR);, Fourier transform infrared spectroscopy insert ignore into journalissuearticles values(FTIR);, UV/visible spectroscopy, and elemental analysis. A total of eight Schiff base compounds insert ignore into journalissuearticles values(3a-6a, 3b-6b); were tested for antimicrobial activity against Escherichia coli ATCC 12228, Staphylococcus aureus ATCC 6538, Klebsiella pneumoniae CCM 2318, Pseudomonas aeruginosa ATCC 27853, Salmonella typhimurium CCM 5445, Enterococcus faecalis ATCC 29212, Bacillus subtilis ATCC 6633, and Candida albicans ATCC 10239 and exhibited a range of activities.
Keywords : Chloralose, ONO tridentate chiral Schiff base, amino sugar, antimicrobial activity