Synthetic strategies towards the carbenoid reactions of ; -acetylenic carbonyls

Authors : Füsun Şeyma KIŞKAN, Emre ÖZGÜZ, Olcay ANAÇ, Nurdan TARAKÇI, Gökçe MEREY

Pages : 1384-1397

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :  Catalytic reactions of α , β ` role=`presentation`> α , β α , β \alpha ,\beta -conjugated carbonyl compounds have been a practical tool towards the synthesis of different useful heterocyclic compounds. Despite the numerous reactions with carbon-carbon double bond conjugated carbonyls, reactions of acetylenic carbonyls are limited. In this study, efficient dioxole synthesis was carried out via acetylenic aldehydes and butadiene formation was preferred over cyclopropene formation via acetylenic esters as different functional groups on these substrates change the product distribution. Both reaction conditions insert ignore into journalissuearticles values(such as solvent and temperature); and electrophilic structure of metal carbenoids alter the product distribution; acceptor insert ignore into journalissuearticles values(A);, donor-acceptor insert ignore into journalissuearticles values(DA);, and acceptor-acceptor insert ignore into journalissuearticles values(AA); functionalized diazo compounds yield different product types over different mechanisms.
Keywords : Acetylenic carbonyl, carbenoid, diazo, butadiene, cyclopropene, Rh 2 OAc, 4, Cu acac, 2