Host/guest inclusion system of surfactants with -cyclodextrin as a viable catalyst for one-pot synthesis of mono - and bis (indolyl)methylmalononitriles in H 2 O

Authors : Fatemeh MIRHASHEMI, Mohammad Ali AMROLLAHI

Pages : 988-996

View : 20 | Download : 11

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :  In this study, encapsulation processes of cetyltrimethylammonium bromide insert ignore into journalissuearticles values(CTAB); or sodium dodecyl sulfate insert ignore into journalissuearticles values(SDS); monomers into the cavity of β ` role=`presentation`> β β \beta -cyclodextrin insert ignore into journalissuearticles values( β ` role=`presentation`> β β \beta -CD); were applied to synthesize mono - and bis insert ignore into journalissuearticles values(indolyl);methylmalononitrile derivatives by a one-pot three-component reaction of an aldehyde, malononitrile, and indole in an aqueous solution. These two inclusion complexes proved to be superior to CTAB or SDS individually, as cationic or anionic surfactants, respectively, for accessing high yields of pure products within shorter reaction times. In addition, simple isolation of products and mild reaction conditions are the other advantages of this green procedure.
Keywords : Conductance, cyclodextrin, encapsulation, inclusion complexes, surfactants