A novel molecular imprinting polymer for the selective adsorption of D-arabinitol from spiked urine

Authors : Yuni RETNANİNGTYAS, Ganden SUPRİYANTO, Ni NYOMAN TRİ PUSPANİNGSİH, Roedi IRAWAN, Siswandono SİSWODİHARDJO

Pages : 1265-1277

View : 19 | Download : 7

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :In this research, molecular imprinting polymers insert ignore into journalissuearticles values(MIPs); for D-arabinitol were synthesized using a bulk polymerization method through a noncovalent approach. The MIPs were prepared by using D-arabinitol as a template, acrylamide as a functional monomer, ethylene glycol dimethacrylateas cross-linker, benzoyl peroxide as an initiator and dimethyl sulfoxideas a porogen. MIPS was synthesized in several formulas with a different molar ratio of template to functional monomers and cross-linker. Fourier-transform infrared spectroscopy insert ignore into journalissuearticles values(FT-IR); and scanning electron microscopy insert ignore into journalissuearticles values(SEM); were used to characterize the MIPs produced. A batch rebinding assay was used to test the binding efficiency of each formula. Batch rebinding test results revealed that MIPsF3 with a molar ratio of the template: monomer and cross-linker ratio respectively insert ignore into journalissuearticles values(1: 4: 25); had the highest binding capacity at 1.56 mgginsert ignore into journalissuearticles values(-1);. The results of isotherm adsorption showed that the MIPs produced followed the Freundlich equation with an R-value of 0.97. The MIPs produced was also selective toward its isomeric compounds insert ignore into journalissuearticles values(i.e. L-arabinitol, adonitol, xylitol, and glucose);. The extraction efficiency of the MIPs against D-arabinitol was 88.98%.
Keywords : MIPs, D arabinitol, bulk polymerization, noncovalent, selective adsorption