Effects of spirulina in arsenic poisoning in the Black Bengal goat

Authors : Amalendu GHOSH, Abdul AWAL, Abu Hadi Noor Ali KHAN, Golam Shahi ALAM, Shafiqul ISLAM, Abu Saleh Mahfuzul BARI

Pages : 63-72

Doi:10.3906/vet-1305-10

View : 15 | Download : 7

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Some of the pharmacological properties of spirulina insert ignore into journalissuearticles values(Spirulina platensis); may be linked to its antioxidant potential, which mitigates oxidative stresses. In this study we examined whether spirulina mitigated arsenic-induced toxicity in the Black Bengal goat insert ignore into journalissuearticles values(Capra hircus);. Nonpregnant female goats of approximately 12 months old were used in noninduced, nontreated control insert ignore into journalissuearticles values(T1);; arsenic-induced, nontreated insert ignore into journalissuearticles values(T2);; and arsenic-induced, spirulina-treated insert ignore into journalissuearticles values(T3); groups. Groups T2 and T3 were given sodium arsenite orally insert ignore into journalissuearticles values(5 mg/kg); daily for 15 weeks. For therapeutic justification of spirulina, 1 group of arsenic-treated goats insert ignore into journalissuearticles values(T3); was given spirulina at 0, 50, 100, and 150 mg/kg daily for another 15 weeks. At the end of the experiment, the goats were sacrificed. The arsenic-treated goats showed the highest arsenic accumulation in the kidneys, followed by the liver, lungs, skin, muscles, and heart. Histological analysis demonstrated fibrosis and lymphocyte infiltration in the liver, degeneration of tubular epithelia and hemorrhage in the kidneys, and keratin deposition in the skin. IgG- and IgM-bearing lymphocytes were unaffected in arsenic toxicosis. Spirulina treatment did not show any significant therapeutic effects on arsenic toxicosis in goat. Therefore, spirulina may not be effective in treating arsenic toxicosis in small animals such as goats.
Keywords : Key words Arsenic, spirulina, Black Bengal goat, kidney