Congenital lymphoma of B-cell lineage in a newborn calf

Authors : Enver BEYTUT, Burhan ÖZBA

Pages : 77-83

View : 16 | Download : 5

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :In this report, congenital lymphoma of B-cell lineage in a Brown Swiss calf is described. A large mass was seen on the head of the calf at birth. At necropsy, multiple masses were found on the skin and internal organs. A histopathological examination showed atypical lymphoid cells separated by connective tissue. None of the tumor cells showed a positive reaction to CD3, but the cells were immunopositive for CD79acy. A CD45+ reaction confirmed a hematopoietic origin of the neoplasm. Tumor cells were also positive for lambda light chain IgG insert ignore into journalissuearticles values(l IgG);. Proliferating cell nuclear antigen insert ignore into journalissuearticles values(PCNA); immunostaining showed diffuse nuclear positivity. Terminal deoxynucleotidyl transferase mediated dUTP nick end labeling insert ignore into journalissuearticles values(TUNEL); staining found numerous apoptotic bodies. The neoplasm was diagnosed as a congenital lymphoma of B-cell lineage.
Keywords : Key words B cell, calf, congenital, lymphoma