Alterations in Some Haematological and Biochemical Parameters in Cattle Suffering from Foot- and -Mouth Disease

Authors : Gürbüz GÖKÇE, Halil İbrahim GÖKCE, Vehbi GÜNEŞ, Hidayet Metin ERDOĞAN, Mehmet ÇİTİL

Pages : 723-727

View : 21 | Download : 5

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The present study was designed to evaluate serum biochemical and haematological parameters and serum nitrate concentrations in cattle suffering from foot- and -mouth disease insert ignore into journalissuearticles values(FMD);. For this purpose, 30 Swiss Brown cattle aged between 3 and 5 years were used. Twenty cattle showed characteristic clinical signs of FMD, whereas the remaining 10 were clinically healthy and used as controls. Peripheral blood samples were collected from both groups and used to establish total white blood cells insert ignore into journalissuearticles values(WBCs);, red blood cells insert ignore into journalissuearticles values(RBCs);, haemoglobin insert ignore into journalissuearticles values(Hb);, and haematocrit insert ignore into journalissuearticles values(PCV);, mean corpuscular volume insert ignore into journalissuearticles values(MCV);, mean corpuscular haemoglobin concentration insert ignore into journalissuearticles values(MCHC); and mean corpuscular haemoglobin insert ignore into journalissuearticles values(MCH);. Serum samples were also collected from these animals and used to establish the concentrations of total protein, albumin, urea nitrogen, creatinin, glucose, calcium, phosphorus, nitrate insert ignore into journalissuearticles values(NO3); and cholesterol and activity of alanine aminotransferase insert ignore into journalissuearticles values(ALT);, aspartate aminotransferase insert ignore into journalissuearticles values(AST); and alkaline phosphatase insert ignore into journalissuearticles values(AP);. There was a significant decrease in the total number of RBCs insert ignore into journalissuearticles values(P < 0.05); and a significant increase in MCV insert ignore into journalissuearticles values(P < 0.05); in cattle with FMD compared to the control group. There were no significant differences in the other haematological parameters evaluated. Serum glucose concentration was significantly higher insert ignore into journalissuearticles values(P < 0.001); in the FMD group than in the control group. Serum total protein insert ignore into journalissuearticles values(P < 0.05);, calcium insert ignore into journalissuearticles values(P < 0.01);, albumin insert ignore into journalissuearticles values(P < 0.001); and cholesterol insert ignore into journalissuearticles values(P < 0.01); levels were significantly low in the FMD group compared to those in the control group. However, there were no significant differences in the other biochemical parameters between the groups. The concentration of serum NO3 was significantly high in the FMD group, suggesting that Aphtovirus induces the production of nitric oxide in vivo.
Keywords : Aphthovirus, biochemistry, cattle, foot and mouth disease, haematology, nitrate