The Effect of Genotype on the Antioxidative Metabolism in Angora Goats

Authors : Ulvi Reha FİDANCI, Fügen TURGAY, Seda ZENGİN

Pages : 975-981

View : 21 | Download : 8

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :In this study, lipid peroxidation, intracellular, membrane and extracellular antioxidant activities in Turkish Angora goats insert ignore into journalissuearticles values(Genotype I); and American x Turkish crossbred Angora goats insert ignore into journalissuearticles values(Genotype II); were investigated, in order to show the effects of genotype on the antioxidative metabolism. Plasma malonlydialdehyde insert ignore into journalissuearticles values(MDA); levels of Angora goats in different genotype were analyzed to show the effects of free radicals. Glutathione peroxidase insert ignore into journalissuearticles values(GSH-Px);, superoxide dismutase insert ignore into journalissuearticles values(SOD); and catalase insert ignore into journalissuearticles values(CAT); activities in hemolysates of erythrocytes were analyzed as intracellular antioxidants, b-carotene in serum as membrane antioxidants and ascorbic acid in plasma, albumin, total bilirubin, glucose, uric acid and ceruloplasmine in serum as extracellular antioxidants to determine the change in the antioxidative metabolism. Plasma MDA levels in American x Turkish crossbred Angora goats insert ignore into journalissuearticles values(Genotype II); were found to be significantly higher than the plasma MDA levels in Turkish Angora goats insert ignore into journalissuearticles values(Genotype I); insert ignore into journalissuearticles values(p < 0.05);. Erythrocyte GSH-Px and SOD activities in American x Turkish crossbred Angora goats insert ignore into journalissuearticles values(Genotype II); were found to be significantly lower than the erythrocyte GSH-Px and SOD activities in Turkish Angora goats insert ignore into journalissuearticles values(Genotype I); insert ignore into journalissuearticles values(p < 0.001);. However, activities of CAT in Turkish x American crossbred Angora goats insert ignore into journalissuearticles values(Genotype II); were found to be significantly higher than the activities of CAT in Turkish Angora goats insert ignore into journalissuearticles values(p < 0.01);. There were no statistically significant differences between the serum b-carotene, plasma ascorbic acid, serum albumin, bilirubin and glucose levels of Angora goats in different genotypes insert ignore into journalissuearticles values(p ? 0.05);. Significant decreases were found both in serum uric acid insert ignore into journalissuearticles values(p < 0.001); and ceruloplasmin insert ignore into journalissuearticles values(p < 0.05); levels of Angora goats in genotype II. It was concluded that improving the productivity by genotypical variation in animal breeding may affect the antioxidative metabolism. The increasing peroxidative metabolism in American x Turkish crossbred Angora goats affected the intracellular antioxidants of the antioxidative metabolism. However, extracellular antioxidant responses were limited to the increasing peroxidative metabolism in genotype II. These findings showed that extracellular and membrane antioxidants are secondary antioxidants.
Keywords : Angora goats, genotype, antioxidative metabolism