Role of Vitamin E in Decreasing the Toxic Effect of Digoxin

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Turkish Journal of Veterinary and Animal Sciences
Volume:23 Issue:5
Role of Vitamin E in Decreasing the Toxic Effect of Digoxin

Role of Vitamin E in Decreasing the Toxic Effect of Digoxin

Authors : İsmail MERAL, Burhanettin BAYDAŞ, Fahri BAYIROĞLU

Pages : 445-450

View : 13 | Download : 7

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :This experiment was carried out to evaluate the role of vitamin E in decreasing the toxic effect of digoxin. Electrocardiographic recordings of New Zealand rabbits which were treated with digoxin-only or digoxin+vitamin E were used. Recordings were obtained before and 24 hours after treatments. It was found that digoxin-only treatment caused a sinusoidal tachicardia without changing the durations or amplitudes of any wave on the trace. However, digoxin+vitamin E treatment did not produce any increase in heart rate. It was concluded that vitamin E injection along with digoxin injection might lower the toxic effect of digoxin. More studies are needed to convince these findings.
Keywords : Digoxin, Vitamin E, Rabbits, Electrocardiogram

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