Lectin and Peptide Expression in Nodose, Sphenopalatine and Superior Cervical Ganglia of The Rat

Authors : Zafer SOYGÜDER

Pages : 489-494

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The presence and distribution of Griffonia SimplicifoliaI-B4 insert ignore into journalissuearticles values(GSA I-B4); and Calcitonin Gene Related Peptide insert ignore into journalissuearticles values(CGRP); were studied in the nodose ganglion insert ignore into journalissuearticles values(NG); insert ignore into journalissuearticles values(inferior ganglion of the vagus nerve);, sphenopalatine ganglion insert ignore into journalissuearticles values(SPG); and superior cervical ganglion insert ignore into journalissuearticles values(SCG); of the rat. GSA I-B4 labeling was found in all ganglia tested. Neither SPG nor SCG cell bodies stained with CGRP were undetectable. The pattern of the distribution of GSA I-B4 and CGRP labeled cells were quite similar in the nodose ganglion. They were found in the poles of the ganglion with some marginal labeling. Large numbers of GSA I-B4 and CGRP labeled cells were found and the number of labeled cells did not vary considerably between the two markers in this ganglion. GSA I-B4 labeled neurons of the SPG and SCG were fewer in numbers compared with NG. These data demonstrate the presence of a `non-peptide` population of unmyelinated primary afferents in sensory and autonomic ganglia with the lack of CGRP immunoreactivity in the autonomic ganglia. This suggests that the `non-peptide` group of primary afferents are involved in different functional mechanisms than peptidergic afferents.
Keywords : lectin, calcitonin gene related peptide, rat, autonomic and sensory ganglia