Combination of amylopectin and chromium form improves energy storage and reduces muscle fatigue in rats during exhaustive exercise

Authors : Mehmet IRMAK, NURHAN ŞAHİN, Cemal ORHAN, Mehmet TUZCU, Patrick Brice Defo DEEH, MELTEM YARDIM, Armağan HAYIRLI, JAMES KOMOROWSKI, Kazim ŞAHİN

Pages : 44-53

View : 23 | Download : 9

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :This study evaluated the effects of amylopectin insert ignore into journalissuearticles values(A); and chromium insert ignore into journalissuearticles values(Cr); forms alone or in combination on energy storage, muscle fatigue-related biochemical markers, and expression of peroxisome proliferator-activated receptors insert ignore into journalissuearticles values(PPAR-γ); and glucose transporter-2 and -4 insert ignore into journalissuearticles values(GLUT-2 and GLUT-4); in rats during exhaustive exercise. Thirty-five male Wistar rats were divided into 5 groups insert ignore into journalissuearticles values(n = 7); as follows: 1); exhaustive exercise insert ignore into journalissuearticles values(E);; 2); E+A; 3); E+A+chromium picolinate insert ignore into journalissuearticles values(CrPic);; 4); E+A+chromium histidinate insert ignore into journalissuearticles values(CrHis);, and 5); E+A+CrPic+CrHis. Rats received 0.0316 g of amylopectin and 11.06 µg of elemental Cr kg$^{-1}$ body weight given as CrPic and CrHis per day. The mean duration of exercise differed insert ignore into journalissuearticles values(55 ± 1.15 vs. 76 ± 1.91); between groups insert ignore into journalissuearticles values(P < 0.05);. Blood glucose level was significantly reduced in the E+A+CrPic+CrHis group compared to the E group. The E+A+CrPic+CrHis group was superior in terms of increasing muscle and liver glycogen contents and blood insulin concentration and of decreasing serum lactate concentration insert ignore into journalissuearticles values(P < 0.05 for all);. However, A and Cr did not alter GLUT-2, GLUT-4, and PPAR-γ expressions. In conclusion, A in combination with supplemental Cr enhanced energy-yielding nutrient conservation and reduced muscle fatigue in exercised rats. They can also help prevent racehorse performance and disability problems.
Keywords : Amylopectin, chromium picolinate, chromium histidinate, exercise, muscle fatigue