Characterization of porcine adiponectin gene (ADIPOQ) polymorphismsand their association with litter size

Authors : Xiaodong ZHANG, Ning ZHOU, Jie ZHOU, Ning WANG, Xiang QIN, Hui DONG, Yueyun DING, Zongjun YIN

Pages : 150-156

View : 13 | Download : 8

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Litter size is one of the most important economic traits for pig production as it is directly related to production efficiency. To evaluate the effects of the adiponectin insert ignore into journalissuearticles values(ADIPOQ); gene on porcine litter size, we investigated ADIPOQ polymorphisms in three breeds, Wannan Black pigs, Berkshire pigs, and BW pigs insert ignore into journalissuearticles values(crossbred pigs produced from mating male Berkshire pigs and female Wannan Black pigs);, using the PCR-SSCP method. Three SNPs insert ignore into journalissuearticles values(c. 178G > A, c. 1165A > G, and c. 1138G > A); were identified. In Wannan Black pigs, association analysis indicated that the c. 178G > A SNP genotype was significantly associated with an effect on total number born insert ignore into journalissuearticles values(TNB; P < 0.05); and the number born alive insert ignore into journalissuearticles values(NBA; P < 0.05); in primiparity. The c.1138G > A SNP was significantly associated with an effect on TNB insert ignore into journalissuearticles values(P < 0.05); and NBA insert ignore into journalissuearticles values(P < 0.05); in primiparity and multiparity. In addition, three of the nine possible genotype combinations, AACC, AACD, and AGCD, were found. AGCD resulted in primiparous and multiparous sows with the highest TNB. These results indicated that polymorphisms in the ADIPOQ gene could be used for marker-assisted selection programs for the genetic improvement of reproductive characteristics in pigs.
Keywords : ADIPOQ gene, polymorphism, litter size, genotype combinations, pig