Formation of local protection of the respiratory tract in Holstein calves

Authors : Yuriy ALEKHIN, Maksim ZHUKOV, Valentina MORGUNOVA, Galina CHUSOVA, İrina KLEMENTEVA

Pages : 656-661

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The processes of formation of the local protection of the respiratory tract in nasal secretion samples of Holstein calves from birth to 6 months of age that were born from clinically healthy cows were examined. Only clinically healthy animals were involved in the experiment. Nasal secretion samples were collected with the help of a sterile foam tampon with a fixing thread in order to assess local immunity in animals at the age of 1, 5, 10, 30, 60, 90, 120, 150, and 180 days. Total protein, mucin, lysozyme activity, and alkaline phosphatase insert ignore into journalissuearticles values(ALP); were determined using commercially available methods. The amounts of immunoglobulins were studied using disk electrophoresis in polyacrylamide gel with commercial marker proteins. Studies have shown that the primary potential of local protection of the respiratory tract is formed during intrauterine development. The main factors of primary potential are mucin, lysozyme, alkaline phosphatase, and secretory immunoglobulins of classes A insert ignore into journalissuearticles values(SIgA); and M insert ignore into journalissuearticles values(SIgM);, which provide safety of adaptation in newborns to the new conditions of existence. There is a decrease in mucin level by 47.3% insert ignore into journalissuearticles values(P 0.05); at the age of 60 days and mucin level increases by 56.7% insert ignore into journalissuearticles values(P < 0.001); between 2 and 6 months.
Keywords : Calves, respiratory tract, local immunity, formation