Morphological and ultrastructural changes in tissues of intermediate and definitive hosts infected by Protostrongylidae

Authors : Abdurakhim Ergashevich KUCHBOEVV, Eric P HOBERG

Pages : 1-7

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Cellular and subcellular mechanisms involved in tissue responses to larval and adult lungworms insert ignore into journalissuearticles values(Protostrongylidae); were respectively explored through experimental and natural infections in molluscan intermediate insert ignore into journalissuearticles values(Xeropicta candacharica); and ruminant definitive hosts insert ignore into journalissuearticles values(Ovis aries);. Reaction to developing larval stages in the gastropod is manifested as cellular infiltration involving lymphocytes and macrophages into the infected tissue, which restricts damage and may result in destruction and elimination of parasites from the intermediate host. Variations in the patterns of localization for infective third-stage larvae in the foot tissue of the intermediate host are described. In the definitive host, evaluation of lung tissue by histology and transmission electron microscopy revealed the activation of lymphocytic and monocytic-macrophage systems. An intensive fibroblastic reaction in the lung parenchyma results in formation of connective-tissue capsules around helminths and more broadly demarcates zones of infected tissue.
Keywords : Key words Protostrongylidae, Xeropicta candacharica, Ovis aries, mollusk tissue, tissue of sheep lung, ultrastructure