The effect of Pistacia terebinthus extract on lipid peroxidation, glutathione, protein, and some enzyme activities in tissues of rats undergoing oxidative stress

Authors : Semra TÜRKOĞLU, Sait ÇELİK, Serhat KESER, İsmail TÜRKOĞLU, Ökkeş YILMAZ

Pages : 82-88

View : 13 | Download : 5

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :This study measures the effects of Pistacia terebinthus flower extract on the amounts of lipid peroxidation insert ignore into journalissuearticles values(LPO);, total protein, glutathione, and enzyme activities in blood. It also measures the effects of the plant extract on glutathione peroxidase insert ignore into journalissuearticles values(GSH-Px); and superoxide dismutase insert ignore into journalissuearticles values(SOD); enzyme activities and it arrives at the conclusion that GSH-Px activity significantly increased in the Pistacia terebinthus-hydrogen peroxide group insert ignore into journalissuearticles values(P < 0.0001); and SOD activity meaningfully increased in the Pistacia terebinthus insert ignore into journalissuearticles values(P < 0.05); and Pistacia terebinthus-hydrogen peroxide insert ignore into journalissuearticles values(P < 0.0001); groups. It is also found that P. terebinthus extract has protective effects against LPO exerted in the kidney, brain, and lungs insert ignore into journalissuearticles values(P < 0.0001);. The positive effects of P. terebinthus extract are also found on the levels of glutathione and total protein in all organs, except for the level of glutathione in the spleen and brain, and the increase of glutathione and total protein insert ignore into journalissuearticles values(P < 0.0001);. These results are parallel to the effect of the extract used in this study on the LPO levels in tissues and they show that the plant species used in the study has positive effects on the activities of antioxidant molecules as well as protective effects against LPO.
Keywords : Pistacia terebinthus, in vivo, enzymes, lipid peroxidation, glutathione, total protein