The assessment of Tp-e interval and Tp-e/QT ratio in patients with morbid obesity before and after laparoscopic sleeve gastrectomy

Authors : Altan AYDIN

Pages : 571-575

Doi:10.18663/tjcl.1343971

View : 41 | Download : 37

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :Aim: Tp-e/QT ratio is a novel marker of ventricular repolarisation. Obesity has been associated with various cardiovascular changes and an increased risk of cardiovascular disease. Obesity may be associated with prolongation of the QT interval, which could potentially increase the risk of ventricular arrhythmias. We aimed to research the assessment of Tp-e interval and Tp-e/QT ratio before and after laparoscopic sleeve gastrectomy insert ignore into journalissuearticles values(LSG); in patients with morbid obesity. Material and Methods: In this study, we enrolled 93 consecutive patients with a BMI >40 kg/m2 or BMI >35kg/m2 with comorbidities who had previously failed to lose weight with conservative methods underwent LSG between January 2012 and December 2016. Results: Heart rate insert ignore into journalissuearticles values(75.7 ± 4.7 vs. 72.8 ± 11.4; p=0.486);, QT interval insert ignore into journalissuearticles values(358.1 ± 32.0 vs. 362.6 ± 30.4; p=0.399); and QTc interval insert ignore into journalissuearticles values(399.0 ± 34.3 vs. 396.2 ± 30.9; p=0.621); were similar before and after LSG. Tp-e interval insert ignore into journalissuearticles values(81.3 ± 11.4 vs. 76.3 ± 10.9; p=0.004);, Tp-e/QT ratio insert ignore into journalissuearticles values(0.23 ± 0.04 vs. 0.21 ± 0.04; p=0.002);, Tp-e/QTc ratio insert ignore into journalissuearticles values(0.20 ± 0.03 vs. 0.19 ± 0.03; p=0.001); were significantly different before and after LSG. Conclusion: Our study showed that morbid obesity may have a negative effect on ventricular repolarization. Substantial weight loss following laparoscopic sleeve gastrectomy in obese patients is accompanied by a significant improvement in ventricular repolarization.
Keywords : Laparoscopic sleeve gastrectomy, morbid obesity, QT interval, Tp e interval, Tp e QT ratio, ventricular repolarization