Old complication, new marker: the relationship between the systemic immune-inflammation index and post-pericardiotomy syndrome.

Authors : Sercan ÇAYIRLI, Berk MUTLU, Ömer Faruk RAHMAN, Sevil GÜLAŞTI, Selim DURMAZ, Hasan GÜNGÖR

Pages : 16-22

Doi:10.56150/tjhsl.1210567

View : 33 | Download : 10

Publication Date : 2023-03-28

Article Type : Research Paper

Abstract :Background: Post-pericardiotomy syndrome insert ignore into journalissuearticles values(PPS); is a common complication after cardiovascular surgery. Post-operative hospitalizations are prolonged due to PPS and mortality is increased due to pericardial effusion leading to cardiac tamponade. Studies have shown that inflammation plays a role in etiology. Objectives: The systemic immune-inflammation index insert ignore into journalissuearticles values(SII); is a new non-invasive marker that has been shown to be effective in predicting inflammatory diseases. In our study, we aimed to investigate the association between the development of PPS and SII in patients undergoing open-heart surgery Methods: Patients who underwent elective open-heart surgery at our institution between 2017 and 2022 were retrospectively studied. Patients who developed PPS and patients who did not develop PPS were included as two different groups in the study. We investigated whether there was a significant difference between the two groups in terms of SII. Results: A total of 228 patients were enrolled in the study, 132 in the patient group and 96 in the control group. The mean age was 63.48 years in the patient group and 65.09 years in the control group and no statistically significant difference was found insert ignore into journalissuearticles values(p 0.34);. There were also no significant differences between the two groups in terms of gender insert ignore into journalissuearticles values(p 0.47);, hypertension insert ignore into journalissuearticles values(p 0.22);, hyperlipidemia insert ignore into journalissuearticles values(p 0.66);, coronary artery disease insert ignore into journalissuearticles values(p 0.76);, diabetes insert ignore into journalissuearticles values(p 0.023);, smoking insert ignore into journalissuearticles values(p 0.35);, and chronic obstructive pulmonary disease insert ignore into journalissuearticles values(p 0.49);. The median value for SII was 568.91 insert ignore into journalissuearticles values(530.17); in the patient group and 634.79 insert ignore into journalissuearticles values(613.23); in the control group, and no significant difference was found between the groups insert ignore into journalissuearticles values(p 0.208);. Statistically significant differences were found in hemoglobin insert ignore into journalissuearticles values(p 0.03);, hematocrit insert ignore into journalissuearticles values(p 0.02);, and glucose insert ignore into journalissuearticles values(p 0.018); values between both groups. Conclusion: The SII is not a useful parameter for predicting post-pericardiotomy syndrome. Comprehensive studies with larger patient populations including subgroup analyzes are needed in this regard.
Keywords : post pericardiotomi syndrome, inflammation, bypass

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