Early Experience of Kidney Transplantation in a New Center

Authors : Murat OZTURK, Atilla SATİR, Bulent GUL, Nizameddin KOCA

Pages : 113-117

Doi:10.46310/tjim.810295

View : 21 | Download : 9

Publication Date : 2020-10-29

Article Type : Research Paper

Abstract :Objective: Kidney transplantation is one of the most important treatments in end-stage renal disease insert ignore into journalissuearticles values(ESRD);. We aimed to share our experiences in 60 insert ignore into journalissuearticles values(57 deceased donors, 3 living donors); kidney transplantation cases performed in our center between July 2017 and August 2020. Material and methods: The demographic data of 60 patients with kidney transplantation performed in our kidney transplant center were evaluated in terms of causes and duration of renal failure human leucocyte antigen insert ignore into journalissuearticles values(HLA); tissue compatibility, immunosuppressive protocol used, antimicrobial agents, rejection status, graft loss, patient loss, postoperative surgical complications. Results: 57 of our kidney transplants were made from deceased donors and 3 from living donors. The mean age of the patients was 44.66 insert ignore into journalissuearticles values(23-68); years. Kidney transplantation was performed in 8 patients insert ignore into journalissuearticles values(13.33%); in the preemptive period. The mean number of mismatches in kidney transplants was 3.95 insert ignore into journalissuearticles values(2-5); and the mean duration of renal replacement therapy insert ignore into journalissuearticles values(RRT); was 54.73 insert ignore into journalissuearticles values(0-270); months. While the mean follow-up period after transplantation was 18.86 insert ignore into journalissuearticles values(2-37); months, it was observed that the mean cold ischemia time was 742.8 insert ignore into journalissuearticles values(60-1080); minutes. Serum creatinine levels of 56 patients with functional grafts at the end of the first month 1.39 insert ignore into journalissuearticles values(0.5-4.9); mg/dL, 54 patients at the end of the sixth month, creatinine levels 1.29 insert ignore into journalissuearticles values(0.56-5.9); mg/dL, The creatinine levels of the 52 patients as of October 2020 were 1.37 insert ignore into journalissuearticles values(0.75-5.16); mg/dL. As surgical complications, hematoma developed in 5 patients insert ignore into journalissuearticles values(8.33%); and lymphocele in 3 patients insert ignore into journalissuearticles values(5%);. Early graft loss developed in one patient with renal artery embolism and two patients with renal vein thrombosis, while chronic rejection developed in two patients. We performed a deceased kidney transplant again 14 months later in a patient who developed graft loss in the early period due to renal vein thrombosis. The kidney inserted later is functional in the 10th postoperative month. One of our patients died due to rhino-orbital mucor mycosis in the postoperative 2nd month, and one patient due to the development of sepsis due to infection in the hip prosthesis in the postoperative 6th month, while another patient died due to myocardial infarction in the postoperative 2nd month. Conclusion: As a result, our kidney transplant center is in development. Our results obtained from 60 kidney transplants, almost all of which were performed from deceased donors, seem to be compatible with the literature. More detailed results can be obtained with the long-term follow-up results and the increase in the number of living donor transplants.
Keywords : Kidney transplantation, Rejection, graft loss