Comparison of Clinical Progress of Covid-19 Patients Followed in the Hospital by Vaccination Status

Authors : Sidelya Ecem YİĞİT, İffet Beril GÖKMEN, Yıldız OKUTURLAR, İftihar KÖKSAL

Pages : 12-16

Doi:10.46310/tjim.1073683

View : 24 | Download : 10

Publication Date : 2022-04-01

Article Type : Research Paper

Abstract :Background: Although Covid-19 vaccines cannot prevent infection with SARS-CoV-2, they do allow infected people to have a milder illness. In unvaccinated people, the disease progresses more severely and the disease can be fatal. Both inactivated insert ignore into journalissuearticles values(Sinovac); and mRNA insert ignore into journalissuearticles values(Biontech-Pfizer); vaccines are used in Turkey. In this retrospective study, clinical course, radiological involvement and some laboratory parameters that are important for Covid-19 were compared in unvaccinated and vaccinated patients who were infected and followed up in the hospital. Material and methods: Patients between the ages of 17-95 who were hospitalized in the Covid-19 isolation wards between June 2021 and November 2021 were included in the study. Various datas of patients were scanned retrospectively from the hospital registry system. Results: While there was no difference in the mean age, highest fibrinogen, D-dimer, ferritin, creatinine, interleukin-6 insert ignore into journalissuearticles values(IL6); values and Covid-19 PCR test negative times besides antibody levels, Group 2 insert ignore into journalissuearticles values(7.8 days); was found to be discharged significantly earlier than Group 1 insert ignore into journalissuearticles values(12.69 days); insert ignore into journalissuearticles values(p=0.046);. There was a significant difference in low-dose thoracic computed tomography insert ignore into journalissuearticles values(CT); findings between the two groups insert ignore into journalissuearticles values(p= 0.023);. Discussion: Our study results showed that regardless of the type of vaccine, vaccination against Covid-19 reduces hospitalization rates, length of stay and prevents serious involvement in the lungs.
Keywords : Covid 19, Sinovac, Biontech, Covid 19 vaccine, IL 6, PCR, SARS CoV 2, CT