A Novel Histological Dataset and Machine Learning Applications

Authors : Kübra UYAR, Merve SOLMAZ, Sakir TASDEMIR, Nejat ÜNLÜKAL

Pages : 185-196

Doi:10.55525/tjst.1134354

View : 18 | Download : 15

Publication Date : 2022-09-30

Article Type : Research Paper

Abstract :Histology has significant importance in the medical field and healthcare services in terms of microbiological studies. Automatic analysis of tissues and organs based on histological images is an open problem due to the shortcomings of necessary tools. Moreover, the accurate identification and analysis of tissues that is a combination of cells are essential to understanding the mechanisms of diseases and to making a diagnosis. The effective performance of machine learning insert ignore into journalissuearticles values(ML); and deep learning insert ignore into journalissuearticles values(DL); methods has provided the solution to several state-of-the-art medical problems. In this study, a novel histological dataset was created using the preparations prepared both for students in laboratory courses and obtained by ourselves in the Department of Histology and Embryology. The created dataset consists of blood, connective, epithelial, muscle, and nervous tissue. Blood, connective, epithelial, muscle, and nervous tissue preparations were obtained from human tissues or tissues from various human-like mammals at different times. Various ML techniques have been tested to provide a comprehensive analysis of performance in classification. In experimental studies, AdaBoost insert ignore into journalissuearticles values(AB);, Artificial Neural Networks insert ignore into journalissuearticles values(ANN);, Decision Tree insert ignore into journalissuearticles values(DT);, Logistic Regression insert ignore into journalissuearticles values(LR);, Naive Bayes insert ignore into journalissuearticles values(NB);, Random Forest insert ignore into journalissuearticles values(RF);, and Support Vector Machines insert ignore into journalissuearticles values(SVM); have been analyzed. The proposed artificial intelligence insert ignore into journalissuearticles values(AI); framework is useful as educational material for undergraduate and graduate students in medical faculties and health sciences, especially during pandemic and distance education periods. In addition, it can also be utilized as a computer-aided medical decision support system for medical experts to minimize spent-time and job performance losses.
Keywords : Classification, Computer aided diagnosis, Histological image, Image processing, Machine Learning