Solvent and moleculer structure effects on acidity strength in non-aqueous medium

Authors : Şule BAHÇECİ, Zafer OCAK, Nuri YILDIRIM, Haydar YÜKSEK

Pages : 27-32

Doi:10.51435/turkjac.939857

View : 15 | Download : 6

Publication Date : 2021-06-29

Article Type : Research Paper

Abstract :The acidic properties of ten 3-alkylinsert ignore into journalissuearticles values(aryl);-4-[3-hydroxy-4-methoxy benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives were investigated. In this study, isopropyl alcohol and tert‐butanol were used as an amphiprotic solvent. Aceton and N,N‐ dimethylformamide insert ignore into journalissuearticles values(DMF); were preferred as a dipolar aprotic solvent. Compounds were titrated with tetrabuthylamonnium hydroxide insert ignore into journalissuearticles values(TBAH); in isopropyl alcohol and titrimetric analyses were used potentiometric method determining the end-points, half-neutralization method determining acidity. Typical S-shaped titration graphs excepted were determined. The acidity strengths of 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives in amphiprotic and dipolar aprotic solvents were calculated using tables and graphs. The pKa values obtained in the solvents were found to be differentiated. The effects of solvent, molecular structure, autoprotolysis constant dielectric constant, and leveling‐differentiation effects of the solvents upon acidity strength of the compounds were discussed.
Keywords : triazole, amphiprotic, pKa, potentiometry