Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?

Authors : İlke KUPELİ, Ufuk KUYRUKLUYILDIZ, Sara TAŞ, Zehra BEDİR, Ayşin SELCAN

Pages : 154-159

Doi:10.5152/clinexphealthsci.2017.413

View : 24 | Download : 25

Publication Date : 2018-09-28

Article Type : Research Paper

Abstract :Objective: Peripheral nerve blocks are now used widely for postoperative analgesia and peripheral nerve catheters are widely utilized. Objective of this study was to investigate effect of perineural infusion of dexmedetomidine on the duration of postoperative analgesia retrospectively. Material & Methods: A total of 60 patients aged between 18 and 65 years were included in the study. Group 1 received infraclavicular patient-controlled perineural bupivacaine insert ignore into journalissuearticles values(0.1 %);. Group 2 received infraclavicular patient-controlled perineural bupivacaine insert ignore into journalissuearticles values(0.1 %); + dexmedetomidine insert ignore into journalissuearticles values(200 mic/100 cc);. Blood pressure, pulse, peripheral oxygen saturation modified ramsay sedation scale, visual pain scores, total amount of analgesics were recorded at the 0, 30, 60, 90 minutes and 2, 4, 6, 8, 12, 24 hours. Results: Systolic blood pressure was higher in Group 1 at the hour 6 insert ignore into journalissuearticles values(p: 0.007);. Whereas, diastolic blood pressure was higher in Group 1 at the hours 4 and 6 insert ignore into journalissuearticles values(p: 0.000, p: 0.003);. Heart rate was found to be higher in Group 2 at the hours 8, 12 and 24 insert ignore into journalissuearticles values(p: 0.004, p: 0.002, p: 0.002);. Patients in Group 1 were found to significantly feel pain and need analgesics at the hours 4 and 6 insert ignore into journalissuearticles values(p: 0.002, p< 0.05);. The mean number of patient requests for analgesia was 5.8±1.4 times in Group 1 and 2.2±0.4 in Group 2 insert ignore into journalissuearticles values(p<0,05);. None of the patients developed sedation/neurological deficits. Conclusion: Perineural infusion of dexmedetomidine combined with bupivacaine was found to increase the duration of postoperative analgesia, reduce 24-hour need for analgesia and have not any adverse efect at low doses.
Keywords : Patient Controlled Analgesia, Perineural Dexmedetomidine infusion, Duration of Postoperative Analgesia