The Relationship Between Gluten Enteropathy and Nail Capileroscopy Findings and Disease Activation

Authors : Burak OKYAR, Abdullah Emre YILDIRIM, Sezgin BARUTÇU

Pages : 760-764

Doi:10.33808/clinexphealthsci.1022573

View : 21 | Download : 9

Publication Date : 2022-09-28

Article Type : Research Paper

Abstract :Objective: Nailfold Videocapilloroscopy insert ignore into journalissuearticles values(NVC); is an examination method that is used as an aid in the diagnosis, follow-up, and treatment strategy of rheumatic diseases such as systemic sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and gives an idea about microcirculation by examining the vascular bed. It is a cheap, easily applicable, and quickly accessible method. Because of these features, we aimed to use the NVC method in patients with Gluten Enteropathy insert ignore into journalissuearticles values(GE); to determine whether this method will be a helpful technique in the diagnosis, activation decision, remission follow-up, and treatment strategy in patients with GE. Methods: In this study, 67 patients diagnosed with GE insert ignore into journalissuearticles values(n=35 disease-active group insert ignore into journalissuearticles values(AGE);, n=32 disease-related remission group insert ignore into journalissuearticles values(RGE);, and control group insert ignore into journalissuearticles values(CG);-27 healthy people whose diagnosis of GE was ruled out were included in this study. Group and CG were divided into ten parameters in capillary pathologies insert ignore into journalissuearticles values(capillary density loss, dilated capillary, giant capillary, microhemorrhage, avascular area, tortuosity, branched capillary, disorganization, extravasation, angiogenesis);. They were divided into two groups as RGE and compared with the results obtained from NVC measurements Results: When patients diagnosed with GE and CG were evaluated in terms of capillary disorder with NVC, While all of the patients with capillary disorders were in the GE group, no capillary disorders were found in the control group insert ignore into journalissuearticles values(p<0.01);. When patients diagnosed with GE were divided into two groups insert ignore into journalissuearticles values(AGE and RGE);, NVC measurements were compared; All patients with capillary disorders were found in the AGE group insert ignore into journalissuearticles values(p<0.01);. Capillary density loss and/or avascular area were detected in 80.9% of patients with capillary disorders. Conclucion: Our study found a statistically significant difference in NVC measurements between GE patients and CG insert ignore into journalissuearticles values(p<0.01);. The fact that all patients with capillary disorders were in the active group in terms of the disease and no capillary disorders were detected in any patients in remission showed that this method could be used as an auxiliary technique in the diagnosis of GE, making the decision of activation or remission, monitoring the disease and determining treatment strategies.
Keywords : CELİAC DİSEASE, VİDEO CAPİLLEROSCOPY, GLUTEN ENTHEROPATHY