Does the Presence of Metabolic Syndrome Alter Serum Uric Acid Concentrations, Pain, and Well-Being in Patient with Chronic Musculoskeletal Pain?

Authors : Şeyda TOPRAK ÇELENAY, Derya ÖZER KAYA, Senem ŞAŞ

Pages : 793-798

Doi:10.33808/clinexphealthsci.832112

View : 21 | Download : 10

Publication Date : 2022-12-30

Article Type : Research Paper

Abstract :Objective: To compare serum uric acid concentrations, pain and well-being in patients having chronic musculoskeletal pain with and without MetS, and investigate cut-off values. Methods: Patients having chronic musculoskeletal pain with insert ignore into journalissuearticles values(MetS group, n=48); and without MetS insert ignore into journalissuearticles values(control group, n=52); were included. The serum uric acid concentration, pain intensity, body composition, physical activity level, quality of life, and psychological status were evaluated by a uric acid blood test, Visual Analogue Scale, Bio-impedance Analyzer, International Physical Activity Questionnaire-7 insert ignore into journalissuearticles values(IPAQ-7);, Nottingham Health Profile, and Hospital Anxiety and Depression Scale, respectively. Results: Uric acid level, fat mass, waist/hip ratio were found higher in the MetS group in comparison to the control group insert ignore into journalissuearticles values(P<0.05);. It was seen that patients in the MetS group had lower physical activity levels than those in the control group insert ignore into journalissuearticles values(P<0.05);. The cut-off points of the uric acid level, fat mass, waist/hip ratio, and physical activity level for detecting MetS were found as 5.25 mg/dl, 37.50 kg, 0.91, and 247.25 METsminutes/week, respectively. Conclusion: Patients with MetS had a greater uric acid level, fat mass, waist/hip ratio, and a lower physical activity level than those without MetS. The increase of uric acid level, fat mass, and waist/hip ratio, and the decrease of physical activity may be critical for patients having musculoskeletal pain with MetS. These results should be considered for the management of these patients.
Keywords : Metabolic syndrome, pain, uric acid, body composition, quality of life