The prevalence of asthma-COPD overlap syndrome in women patients with biomass fuel utilizing

Authors : Burcu YORMAZ
Pages : 11-18
Doi:10.26900/hsq.1.1.03
View : 29 | Download : 6
Publication Date : 2021-04-30
Article Type : Research Paper
Abstract :Asthma-chronic obstructive pulmonary disease overlap insert ignore into journalissuearticles values(ACO); indicates that its characteristics with pulmonary exaggerated reactivity and airflow limitation chronically. We aimed to investigate the differences among women non smoker participants who have asthma, chronic obstructive pulmonary disease insert ignore into journalissuearticles values(COPD); and ACO with biomass smoke exposure. Patients were examined at the outpatient clinic from September 2017 to March 2020. Non-smoker women patients aged ≥40 years, diagnosed with obstructive pulmonary disease were included in the study. pulmonary function tests insert ignore into journalissuearticles values(PFT);, early reversibility testing insert ignore into journalissuearticles values(bronchodilator test);, and sputum eosinophil analysis were performed to all patients. A total of 102 patients were included. The mean age was 46.95±9.50 years. In the differential diagnosis, 65 patients insert ignore into journalissuearticles values(63.7%); had asthma and 37 patients insert ignore into journalissuearticles values(36.3%); had COPD. Among COPD patients, 10 insert ignore into journalissuearticles values(27.0%); were diagnosed with ACO. The actual prevalence rates of COPD and ACO were 26.5% and 9.8%, respectively. Poisson regression analysis showed that COPD compared to asthma, while holding the others variable constant in the model, are expected to have 2.976 times greater rate for exacerbations. insert ignore into journalissuearticles values(IRR, 95% CI, 2.976 insert ignore into journalissuearticles values(0.687 to 1.494);, 5.296 insert ignore into journalissuearticles values(1.203 to 2.130);, P<0.001, Coef. 1.091, 1.667 respectively);. Logistic Regression analysis demonstrated that, the count of sputum, blood eosinophil and total IgE results were correlated with the exacerbation times. Biomass smoke exposure in the women population is revealed as a significant factor for the diagnosis of ACO.
Keywords : Chronic obstructive pulmonary disease, asthma, asthma COPD overlap, biomass smoke

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