Reproducibility of choroidal thickness measurements in hemodialysis patients: A spectral domain optical coherence tomography study

Authors : Mehmet Murat UZEL, Özgür EROĞUL, Leyla ERYİĞİT EROĞUL, Ayşe Güzin TAŞLIPINAR UZEL, Avşin İBİŞ, Hamidu Hamisi GOBEKA

Pages : 39-44

View : 31 | Download : 3

Publication Date : 2022-01-27

Article Type : Research Paper

Abstract :Aside from general body fluid fluctuation, hemodialysis insert ignore into journalissuearticles values(HD); may cause changes in ocular fluid balance, resulting in changes in subfoveal choroidal thickness insert ignore into journalissuearticles values(SFCT); and other ocular parameters. As a result, the purpose of this study was to investigate the effects of hemodialysis on the reproducibility of SFCT measured by spectral domain-optical coherence tomography insert ignore into journalissuearticles values(SD-OCT);. Twenty-six HD insert ignore into journalissuearticles values(26 eyes); patients had their pre- and post-HD SFCT measured, and the results were compared for reproducibility. Following a thorough ophthalmic examination, SD-OCT was performed three times in a row during a single session. The same physician measured SFCT after automatically identifying choroid with a software caliper. Reproducibility parameters, including intra-class correlation coefficients insert ignore into journalissuearticles values(ICCs);, coefficients of variation insert ignore into journalissuearticles values(COV);, and test-retest variability insert ignore into journalissuearticles values(TRTV); were then calculated. Males made up 53.85% of the 26 HD patients. There was a significant IOP difference between pre-HD insert ignore into journalissuearticles values(16.42±3.14 mmHg); and post-HD insert ignore into journalissuearticles values(14.21±2.78 mmHg); insert ignore into journalissuearticles values(P<0.001);. SFCT decreased significantly from pre-HD 243.50±10.23 μm to post-HD 234.29±9.41 μm insert ignore into journalissuearticles values(P<0.001);. ICC value increased significantly after HD, rising from 0.948 to 0.989 insert ignore into journalissuearticles values(P<0.001, for all);. Pre- and post-HD COV values were 1.6% and 0.65%, respectively. Also, pre- and post-HD TRTV values were 7.864±1.996 μm and 3.074±1.536 μm, respectively. In this study, the reproducibility of SFCT as measured by OCT was lower during pre-HD compared to post-HD. Post-HD SD-OCT assessment appears to improve the reliability of clinical outcomes in the diagnosis and monitoring of HD patients.
Keywords : Hemodialysis, spectral domain optical coherence tomography, subfoveal chorodial thickness, reproducibility

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