Assessment of plasma lipid parameters, exhaled nitric oxide fraction, and systemic immune-inflammation index on stable asthma patients

Authors : Muhammed Emin DÜZ, Aydın BALCI

Pages : 101-109

View : 30 | Download : 3

Publication Date : 2022-04-24

Article Type : Research Paper

Abstract :Asthma is a chronic disease characterized by the presence of inflammatory agents in the airways, and diagnosis and treatment are based on clinical questioning, physical examination, laboratory results, and spirometric analysis. This study investigated the effect of asthma alone on routine laboratory parameters in adults and whether an idea about the course of the disease can be obtained using these parameters. Two hundred and fourteen patients with known asthma history, diagnosed, and treated according to guidelines, were included in our study. Among all patients and between gender-specific groups, total cholesterol insert ignore into journalissuearticles values(CHOL);, HDL, LDL, VLDL, triglyceride insert ignore into journalissuearticles values(TG);, albumin, total protein insert ignore into journalissuearticles values(TP);, lactate dehydrogenase insert ignore into journalissuearticles values(LDH);, glucose, urea, creatinine, C reactive protein insert ignore into journalissuearticles values(CRP);, FeNO, SII, INR, and complete blood count value parameters of the patients were analyzed. When we consider all asthma patients, we found that the mean glucose, LDH, CRP, TG, FeNO, and INR values outpaced the upper limit of the reference range. In contrast, the mean HDL value was below the reference range for all patients. In addition, our study found a significant correlation between triglyceride levels within the biochemical parameters with FeNO and SII);. Finally, when we compared the mean values of gender-specific groups, we found a statistically significant difference between VLDL, HDL, TG, CRP, FeNO, creatinine, lymphocyte, eosinophile, basophile, and hemoglobin. CRP, LDH, TG, FeNO, SII, and INR levels may help clinicians in adult patients with stable asthma. In addition, differences depending on gender could be observed in the biochemical parameters of asthma patients.
Keywords : Asthma, biochemistry, adult, laboratory

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