Role of Platelet Mass Index in the Differential Diagnosis of Patients with Elevated Prostate-Specific Antigen Levels

Authors : Halil Ferat ÖNCEL, Remzi SALAR, Engin ÖZBAY, Emine Zeynep TARİNİ

Pages : 16-20

Doi:10.37990/medr.944806

View : 19 | Download : 11

Publication Date : 2022-01-01

Article Type : Research Paper

Abstract :Aim: To evaluate the role of platelet mass index insert ignore into journalissuearticles values(PMI); calculated using hemogram parameters obtained from a routine blood test in the differentiation of prostate cancer in patients with prostate-specific antigen insert ignore into journalissuearticles values(PSA); values of 2.5-10 ng/dl. Material and Method: Seventy-five patients with prostate cancer and 48 with prostatitis were included in the study and grouped according to their pathology results. The white blood cell insert ignore into journalissuearticles values(WBC);, hemoglobin insert ignore into journalissuearticles values(HGB);, thrombocyte insert ignore into journalissuearticles values(PLT);, neutrophil-lymphocyte ratio insert ignore into journalissuearticles values(NLR);, platelet-lymphocyte ratio insert ignore into journalissuearticles values(PLR);, mean platelet volume insert ignore into journalissuearticles values(MPV); and PMI values were compared between the two groups. Results: The PMI and PLT levels of the prostate cancer group were statistically significantly lower than those of the prostatitis group insert ignore into journalissuearticles values(p<0.05);. In predicting prostate cancer, the cut-off value for the PMI level was determined as 1.480, at which the likelihood ratio was calculated as 1.08. Conclusion: We consider that PMI calculated using hemogram parameters in patients with a PSA value below 10 ng/dl will guide the clinician in differentiating prostate cancer from other prostate pathologies without performing an unnecessary biopsy.
Keywords : prostate specific antigen, platelet mass index, prostate cancer