Assessment of Thyroid Function Tests in Patients with COVID-19 Infection and Their Relationship with Euthyroid Sick Syndrome

Authors : Hümeyra ASLANER, Ali Ramazan BENLİ, Adil ÇETİN, Zeliha KAYA ERTEN, Selçuk MISTIK, Yasin ŞİMŞEK

Pages : 90-94

Doi:10.37990/medr.982352

View : 25 | Download : 9

Publication Date : 2022-01-01

Article Type : Research Paper

Abstract :Aim: Thyroid functions are affected by many factors functions such as some infections and drugs. This study aimed to investigate how the thyroid function tests were affected after COVID-19 infection and their relationship with euthyroid sick syndrome. Material and Method: Our study was designed as a retrospective and case-control study. The participants consisted of two groups as the control and patient groups. Thyroid function tests insert ignore into journalissuearticles values(TFT);, hemogram and routine biochemistry of the groups were assessed. In addition, the tests of the patient group within the last 6 months before the infection were assessed. The patients’ symptoms, presence of a chronic disease, smoking history, and clinical status during COVID-19 infection were recorded. Results: A total of 473 people were included in the study. Of the participants, 54.5% were female. The white blood count insert ignore into journalissuearticles values(WBC);, hemoglobin insert ignore into journalissuearticles values(HGB);, platelet insert ignore into journalissuearticles values(PLT);, and neutrophil insert ignore into journalissuearticles values(NEU); counts were higher in the patient group. Lymphocyte insert ignore into journalissuearticles values(LY); and mean platelet volume insert ignore into journalissuearticles values(MPV); counts were similar. Tyroid stimulating hormone insert ignore into journalissuearticles values(TSH); and triiodothyronine insert ignore into journalissuearticles values(T3); values of the patients were higher compared with the control group. The thyroxine insert ignore into journalissuearticles values(T4); level was similar in the two groups.TSH, T3 and T4 levels of the patient group before COVID-19 were higher than the results just after the quarantine process after COVID-19 infection. Conclusion: Thyroid dysfunction develops in COVID-19 patients within the course of the disease. This condition can be partially explained with the euthyroid sick syndrome. It is also possible with the thyroid gland being the direct or indirect target of the virus. 
Keywords : Euthyroid Sick Syndrome, Thyroid Dysfunction, Covid 19