Cellular Response of Cancer to Music: Mirror, Mirror, on the Wall, Which is the Most Effective of Them All?

Authors : Ceren ELBE, Melike ÖZGÜL ÖNAL, Gürkan YİĞİTTÜRK, Seda GELEN TURAN, Hülya ELBE

Pages : 237-43

Doi:10.37990/medr.1173999

View : 20 | Download : 51

Publication Date : 2023-05-15

Article Type : Research Paper

Abstract :Aim: Cancer is one of the most common health problems in the world. Music is a therapy method that creates positive changes in human behavior. This study aims to examine the effects of Turkish and Western classical music on MCF-7, SKOV-3, PC-3, U87, and COLO741 cancer cell lines. Material and Methods: Group 1: No sound, Group 2: Turkish classical music insert ignore into journalissuearticles values(ney);, Group 3: Western classical music insert ignore into journalissuearticles values(piano);, and Group 4: Western classical music insert ignore into journalissuearticles values(violin);. After listening to the cancer cells for 40 min, the audio files were interrupted for 1h, and then music was played for another 40 min. The effect of music on the proliferation of cancer cells was determined by WST-1 cell viability analysis. Statistical analyzes were performed with the SPSS program. Results: There was no statistically significant difference between the groups that were applied music once in only the MCF-7 breast cancer cells and the control group insert ignore into journalissuearticles values(p>0.05);. A statistically significant decrease was detected in cell viability when the control group and the other groups that were applied to music twice were compared insert ignore into journalissuearticles values(p<0.05);. For other cancer cell lines except insert ignore into journalissuearticles values(please the SKOV-3 ovarian cancer cells, it was determined that music application once also caused a statistically significant decrease in cell viability insert ignore into journalissuearticles values(p<0.05);. Conclusion: We determined that classical music effectively reduced and suppressed the number of cancer cells. According to the data, Turkish and Western classical music can be used to support the treatment in of cancer patients.
Keywords : Breast cancer, prostate cancer, colon cancer, ovarian cancer, glioblastoma, turkish classical music, western classical music