The Effect of Vaginal Bleeding in Early Pregnancy on First Trimester Screening Test, Uterine Artery Doppler Indices and Perinatal Outcomes

Authors : Meriç BALIKOĞLU, Burak BAYRAKTAR, Azra ARICI YURTKUL, Mehmet ÖZEREN

Pages : 393-9

Doi:10.37990/medr.1196046

View : 12 | Download : 5

Publication Date : 2023-05-15

Article Type : Research Paper

Abstract :Aim: We aimed to prospectively investigate the effect of first trimester vaginal bleeding on first trimester screening test, uterine artery insert ignore into journalissuearticles values(UtA); Doppler results and perinatal outcomes. Material and Methods: Fifty cases that presented with vaginal bleeding in the first trimester between 2019 and 2020 constituted the early vaginal bleeding insert ignore into journalissuearticles values(abortus imminens-threatened abortion); group and fifty cases without a history of vaginal bleeding in pregnancy constituted the control group. Demographic datas were noted at the first visit. Both groups were followed up until birth. First trimester screening test insert ignore into journalissuearticles values(double screening test); between 11-14 weeks and UtA Doppler examination between 20-24 weeks of gestation was performed. Perinatal outcomes and values of nuchal translucency insert ignore into journalissuearticles values(NT);, free β human chorionic gonadotropin insert ignore into journalissuearticles values(f β-hCG);, pregnancy-associated plasma protein A insert ignore into journalissuearticles values(PAPP-A);, and UtA Doppler were compared between the two groups. Results: There was no statistically significant difference was found between the two groups in terms of NT and PAPP-A among the first trimester screening test results insert ignore into journalissuearticles values(p=0.741 and p=0.937, respectively);. In the group with threatened miscarriage, f β-hCG value was numerically higher, but there was no statistically significant difference insert ignore into journalissuearticles values(1.24±0.59 vs. 1.1±0.93, p=0.057);. In the Doppler examination of the UtA, there was no statistically significant difference between the groups in terms of systolic/diastolic ratio, pulsatility index, resistive index and the presence of a notch insert ignore into journalissuearticles values(p=0.713, p=0.528, p=424, p=0.538, respectively);. Perinatal complication rate was statistically significantly higher in the study group insert ignore into journalissuearticles values(p=0.013; Odds Ratio:3.2, 95% CI 1.2-8.3);. Conclusion: Contrary to some different studies, we believe that first trimester screening test parameters or uterine artery Doppler flow indices do not have a place in predicting perinatal outcomes of pregnant women with a history of vaginal bleeding in the first trimester. In addition, early vaginal bleeding does not significantly affect screening parameters. Perinatal complication rate was found to be statistically significantly higher in the group with a history of threatened miscarriage.
Keywords : Doppler, uterin arter, abortus imminens, düşük tehditi, vajinal kanama, ilk trimester