Comparison of Cardiovascular Disease Risk Indicators in Bipolar Disorder Patients with Healthy Controls

Authors : Yaşar KAPICI, Selçuk AYHAN, Bulut GUC, Atilla TEKİN

Pages : 320-5

Doi:10.37990/medr.1232186

View : 13 | Download : 8

Publication Date : 2023-05-15

Article Type : Research Paper

Abstract :Aim: It is important to assess the likelihood of cardiovascular disease in patients with bipolar disorder insert ignore into journalissuearticles values(BD);. In this study, indicators of increased cardiovascular disease risk on electrocardiogram insert ignore into journalissuearticles values(ECG); and laboratory were evaluated. Material and Methods: In the present investigation, we studied the demographic details, ECG variables, and blood test results of 90 healthy controls insert ignore into journalissuearticles values(HC); and 97 patients we followed for BD diagnosis. Results: Age and gender trends were similar between the BD and HC groups insert ignore into journalissuearticles values(p=0.844 and p=0.664);. BD had a higher mean number of fragmented QRS insert ignore into journalissuearticles values(fQRS); than the HC group, and fQRS was more frequent insert ignore into journalissuearticles values(p=0.002 and p=0.007);. The frontal QRS-T angle was wider in the BD group than it was in the HC group insert ignore into journalissuearticles values(p=0.038);. Monocyte-to-lymphocyte ratio insert ignore into journalissuearticles values(MLR);, monocytes to high-density lipoprotein cholesterol insert ignore into journalissuearticles values(HDL-C); ratio insert ignore into journalissuearticles values(MHR);, and atherogenic index of plasma insert ignore into journalissuearticles values(AIP); were statistically greater in BD patients insert ignore into journalissuearticles values(p=0.021, p<0.001, and p<0.001);. Conclusion: In brief, the report indicates that impaired ventricular repolarization is related to an elevation in the frontal QRS-T angle in BD. As a result, BD patients have a greater risk of cardiovascular mortality and ventricular arrhythmias. As a result, clinicians ought to have a greater understanding of the frontal QRS-T angle and conduct an ECG examination on regular controls.
Keywords : Bipolar disorder, frontal QRS T angle, fragmented QRS