Relationship Between Chronic Spontaneous Urticaria and Fibromyalgia Syndrome

Authors : Sevgi KULAKLI, Işıl Deniz OĞUZ, İlker Fatih SARI, Halil ÖĞÜT

Pages : 638-43

Doi:10.37990/medr.1284145

View : 33 | Download : 38

Publication Date : 2023-09-18

Article Type : Research Paper

Abstract :Aim: Autoimmunity, peripheral nerve dysfunction, and neurogenic inflammation are common mechanisms in chronic spontaneous urticaria insert ignore into journalissuearticles values(CSU); and fibromyalgia syndrome insert ignore into journalissuearticles values(FMS);. We aimed to detect the prevalence of FMS in patients with CSU and to determine whether this prevalence was affected by the severity of urticaria, and dermatology life quality. Material and Methods: Fifty-three patients with CSU and 49 controls were enrolled in this prospective, controlled, cross-sectional study. The severity of CSU was assessed using Urticaria Activity Scores insert ignore into journalissuearticles values(UAS);, and Dermatology Life Quality Index insert ignore into journalissuearticles values(DLQI); scores were recorded. The 2016 fibromyalgia diagnostic criteria were used for the diagnosis of FMS, and FMS-related functional disability was assessed using the Fibromyalgia Impact Questionnaire insert ignore into journalissuearticles values(FIQ);. Results: Fibromiyalgia prevalence and the FIQ scores were higher in the CSU group than in the control insert ignore into journalissuearticles values(p=0.033 and p=0.004, respectively);. There was no statistically significant difference between the urticaria durations and UAS of CSU with and without FMS insert ignore into journalissuearticles values(p>0.05);, but DLQI scores were statistically significantly higher in CSU with FMS insert ignore into journalissuearticles values(p=0.007);. A statistically significant moderate positive correlation was present between DLQI and FIQ, Widespread Pain Index, and Symptom Severity Scale scores insert ignore into journalissuearticles values(r=0.500, r=0.408, r=0.469, r=0.507, respectively);. Conclusions: The prevalence of FMS and the disability due to FMS was increased in CSU. Furthermore, the FMS prevalence was not affected by the duration and severity of urticaria; however, it was associated with decreased quality of life.
Keywords : fibromiyalgia syndrome, chronic urticaria, quality of life