Investigation of Age- and Gender-Related Changes in Anatomical Variables of the Cerebellum in Healthy Adults Using MR Imaging

Authors : Gülçin Ray, Abdullah Ray, İbrahim Kürtül, Saadet Erdem, Basel Malaysheh

Pages : 234-239

Doi:10.37990/medr.1595432

View : 55 | Download : 67

Publication Date : 2025-01-15

Article Type : Research Paper

Abstract :Aim: The aging process and gender are thought to cause changes in anatomical regions of the brain. The present study was designed to present age- and gender-related changes in the morphometric characteristics of the cerebellum, which is known to be mainly responsible for the coordination of the skeletal system and balance. Material and Method: Brain magnetic resonance (MR) images of healthy individuals aged 25-55 years were analyzed. MCRae line (MCL), Klaus index (KI), clivus length (LC), supraocciput length (LSO), diameter of the posterior cranial fossa (PDFC), height of the posterior cranial fossa (PHFC), lateral diameter of the cerebellum (LDC), cerebellum height (HCL), cerebellum width (WCL), cerebrum height (HC), anterior dural angle of the cerebellum (ADAC), angle of the cerebellar clivus (ACC), anteroposterior diameter of the right cerebellar hemisphere (RCHD) and anteroposterior diameter of the left cerebellar hemisphere (LCHD) variables were measured. Results: It has been determined that the difference between the groups for age, MCL, LSO, PHFC, HCL variables is statistically significant. The difference between genders is statistically significant for KI, LC, PHFC, LDC, WCL, HC, RCHD, LCHD variables in the first group, MCL, KI, LDC, HC, LCHD variables in the second group, LC, LDC, HCL, WCL, HC, ACC, LCHD variables in the third group. Conclusion: Overall, the results show that aging and gender cause changes in cerebellum morphometry in healthy individuals for the Bolu (Türkiye) population.
Keywords : Cerebellum, magnetic resonance imaging, morphometry, sex differences, brain