Effects of Dietary-Like Amount of Arginine Supplementation on Fractional Exhaled Nitric Oxide (FeNO) Levels in Obese and Normal-Weight Individuals

Authors : Neslihan Öner, Eda Köksal

Pages : 79-87

Doi:10.55517/mrr.1385986

View : 47 | Download : 73

Publication Date : 2024-06-30

Article Type : Research Paper

Abstract :Aim: In previous studies, the arginine-nitric oxide pathway has been associated with pathways specific to some chronic diseases such as obesity. The purpose of this study was to examine the effects of dietary-like amounts of arginine supplementation on fractional exhaled nitric oxide (FeNO) levels in obese and normal-weighted individuals. Methods: This study was conducted with 40 participants (20 obese and 20 control). The participants consumed 4500 mg arginine supplement and low protein (41 mg arginine/25 g powder product) soup after one-night hunger. Resting metabolic rate (RMR) and 1st, 2nd, and 5th hour fractional exhaled nitric oxide (FeNO) levels were measured and 3-day food consumptions were recorded. Results: There was no significant difference between the mean baseline and 1st -hour FeNO level of the participants in the obese group and the mean baseline FeNO level of the participants in the control group. The mean 2nd and 5th hour FeNO level of the participants in the control group were significantly higher than the mean 2nd and 5th hour FeNO levels of the participants in the obese group (p<0.05). Conclusion: The fact that normal-weighted participants had higher FeNO levels than obese participants probably support previous studies that pointed to the relationship between airway inflammation and obesity.
Keywords : Arjinin, Obezite, Solunum, Nitrik oksit, Vücut ağırlığı