Evaluation of Cerebrospinal Fluid Results in Patients Presenting with a Prediagnosis of Meningitis

Authors : Esra AKYÜZ ÖZKAN, Yeliz TANRIVERDİ ÇAYCI

Pages : 234-237

Doi:10.33631/sabd.1203008

View : 20 | Download : 12

Publication Date : 2023-05-10

Article Type : Research Paper

Abstract :Aim: It was aimed to determine the microorganisms and antibiotic susceptibilities obtained from cerebrospinal fluid samples insert ignore into journalissuearticles values(CSF);. Material and Methods: CSF samples of 138 patients who admitted with a prediagnosis of meningitis to Ondokuz Mayıs University Pediatric Emergency Department between 01/01/2021-01/01/2022 was included. CSF cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 insert ignore into journalissuearticles values(bioMeriux, France); automated identification system. If the growth was detected by blood culture system, the specimen was cultivated onto the 5% blood agar, Eosin Methylene Blue agar and chocolate agar. Also, CSF samples were studied for both viral and bacterial agents with the Smart Cycler insert ignore into journalissuearticles values(Cepheid, USA); device working with Real-Time PCR method. In this system, Streptococcus pneumoniae, Neisseria meningitidis, Haemophilus influenzae, Cytomegalovirus, Herpes simplex type-1, Herpes simplex type-2, Human herpes virus type-6 insert ignore into journalissuearticles values(HHV-6);, Varicella zoster virus and Epstein Barr virus agents were detected. Results: Of the 138 CSF samples, 50,88% were male and 49,12% were female. The mean age of the patients was 36 ± 55 months. Bacterial agents were detected in 18 insert ignore into journalissuearticles values(13,8%); of the CSF samples and viral agents in 12 insert ignore into journalissuearticles values(9,2%); samples. Staphylococcus epidermidis insert ignore into journalissuearticles values(64.6%);, Staphylococcus aureus insert ignore into journalissuearticles values(7.7%); and Streptococcus pneumonia insert ignore into journalissuearticles values(6.9%); took the first three places in bacterial agents. Among the viral agents, HHV-6 was the most common followed by Enteroviruses. Conclusion: It has been observed that the profiles and resistance status of microorganisms frequently seen in CSF have changed over the years.
Keywords : menenjit, beyin omirilik sıvısı, antimikrobiyal duyarlılık, PCR