COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN

Authors : Merve Demir Özkan, Süleyman Salman, Mücahit Furkan Balcı, Abdulmecit Öktem, Mustafa Şanlı, Yasemin Alan, Murat Alan

Pages : 11-16

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Publication Date : 2025-04-30

Article Type : Research Paper

Abstract :This study aimed to examine the levels of 25 hydroxy vitamin D (25-OH D) in preeclampsia and normotensive pregnant groups. A total of 70 pregnant women who came to the Health Sciences University, Istanbul Gaziosmanpasa Training and Research Hospital for delivery at 35-40 weeks of gestation were included in the study. The study group consisted of 35 preeclamptic (n=35) and 35 normotensive (n=35) pregnant women. Demographic, obstetric, and laboratory results of the two groups were compared in terms of 25-OH D levels. There was no statistically significant difference with the control group in terms of maternal age, gestational age at birth, gravidity, parity, number of abortions and living children, and BMI (p>0.05). When the mean diastolic blood pressure and systolic blood pressure of the groups were compared, the mean blood pressure of the individuals in the preeclamptic group was found to be statistically and significantly higher than the mean systolic and diastolic blood pressure of the individuals in the control group (p<0.05). When the groups were compared in terms of LFT (ALT, AST), proteinuria in urine, and platelet levels in blood, no statistically significant difference was found between the groups. Vitamin D levels were found to be statistically significantly lower in preeclamptic pregnancies compared to normotensive pregnancies. Low maternal vitamin D levels may play a role in the etiology of essential hypertension and preeclampsia, and more comprehensive research is needed on the potential positive effects of additional vitamin D supplementation.
Keywords : Complications, Hypertension, Preeclampsia, Pregnancy, Vitamin D.